# OPKO Health Inc. (OPK) fundamentals

Data as of 2026-09-08. NASDAQ, United States. Sector: Healthcare / Biotechnology. Price $1.64, market value $1.2 billion.

## Valuation
- **P/E (trailing): n/a** (negative earnings). OPKO Health Inc. reported negative earnings over the last twelve months, so the P/E is not meaningful; use price-to-sales, EV/EBITDA and free-cash-flow yield instead.
- **Price / sales: 2.1×**. Each dollar of revenue is priced at 2.1×.
- **Price / book: 1.0×**. The shares trade at 1.0× book value; book value is a meaningful part of the valuation.
- **EV / EBITDA: 20.8×**. Enterprise value is 20.8× operating earnings before depreciation, the multiple that ignores how the company is financed; above 20× is demanding.
- **Free-cash-flow yield: -10.9%** (5-yr avg -11.5%). Free cash flow is negative: the business is consuming cash, which is normal for heavy investment phases but a warning otherwise.

## Profitability
- **Gross margin: 40.8%**. OPKO Health Inc. keeps 40.8% of revenue after the direct cost of what it sells.
- **Operating margin: -8.2%**. Operating margin is negative: the business loses money before interest and tax.
- **Net margin: -37.2%**. The company reported a net loss over the last twelve months.
- **Return on equity: -17.8%**. Return on equity is negative because earnings are negative.
- **Return on invested capital: -4.2%**. Return on all capital, debt included, is -4.2%: close to or below the cost of capital, so growth may not create value.
- **Return on assets: -3.8%**. Each dollar of assets produces -3.8% of profit.

## Growth
- **Revenue growth (1 yr): -14.9%** (3-yr -15.5%/yr, 5-yr -15.8%/yr). Revenue fell 14.9% over the last year, against -15.8% a year compounded over five years: growth is accelerating.
- **EPS growth (1 yr): -275.0%**. Earnings per share fell 275.0%, slower than revenue, so margins compressed.

## Financial health
- **Debt to equity: 0.00**. Debt is 0.00 times equity: a conservative balance sheet.
- **Net debt / EBITDA: net cash**. OPKO Health Inc. holds more cash than debt.
- **Altman Z-score: 2.14**. A Z-score of 2.14 is in the grey zone; not distressed, not clearly safe.
- **Piotroski F-score: 3/9**. 3 of 9 checks pass: weak or deteriorating financials.

## Dividends
- **Dividend: none**. OPKO Health Inc. does not currently pay a dividend.

## Price and momentum
- **Total return (1 yr): 18.8%** (YTD 30.2%, 3-mo 13.9%). The shares are up 18.8% over twelve months including dividends.
- **From 52-week high: -5.2%** (67.3% above the low). Trading 5% below its 52-week high.
- **200-day average: above**. The price sits above its 200-day moving average, the usual definition of an uptrend.
- **RSI (14-day): 66**. An RSI of 66 is neutral.
- **Beta (1 yr): 0.89** (volatility 54%). Beta of 0.89 against the S&P 500: the shares move roughly with the market.

Live score and charts: https://foliofundamentals.com/analyzer?s=OPK · Page: https://foliofundamentals.com/stocks/opk

Not investment advice.