# Pyxis Oncology Inc. (PYXS) fundamentals

Data as of 2026-09-08. NASDAQ, United States. Sector: Healthcare / Biotechnology. Price $3.89, market value $324 million.

## Valuation
- **P/E (trailing): n/a** (negative earnings). Pyxis Oncology Inc. reported negative earnings over the last twelve months, so the P/E is not meaningful; use price-to-sales, EV/EBITDA and free-cash-flow yield instead.
- **Price / sales: 23.4×**. Each dollar of revenue is priced at 23.4×, a level that requires very high margins or very fast growth to justify.
- **Price / book: 21.6×**. The shares trade at 21.6× book value; most of the value is in earnings power and intangibles rather than the balance sheet.

## Profitability
- **Operating margin: -609.2%**. Operating margin is negative: the business loses money before interest and tax.
- **Net margin: -574.5%**. The company reported a net loss over the last twelve months.
- **Return on equity: -149.1%**. Return on equity is negative because earnings are negative.
- **Return on assets: -87.0%**. Each dollar of assets produces -87.0% of profit.

## Growth
- **Revenue growth (1 yr): -14.2%**. Revenue fell 14.2% over the last year.
- **EPS growth (1 yr): 3.0%**. Earnings per share rose 3.0%, faster than revenue, so margins expanded or the share count shrank.

## Financial health
- **Current ratio: 3.41** (quick 3.41). Current assets cover the next year's liabilities 3.41 times.
- **Altman Z-score: 3.70**. A Z-score of 3.70 places the company in the safe zone for bankruptcy risk.
- **Piotroski F-score: 2/9**. 2 of 9 checks pass: weak or deteriorating financials.

## Dividends
- **Dividend: none**. Pyxis Oncology Inc. does not currently pay a dividend.

## Price and momentum
- **Total return (1 yr): 141.6%** (YTD 238.3%, 3-mo 118.5%). The shares are up 141.6% over twelve months including dividends.
- **From 52-week high: -29.9%** (277.7% above the low). Trading 30% below its 52-week high.
- **200-day average: above**. The price sits above its 200-day moving average, the usual definition of an uptrend.
- **RSI (14-day): 64**. An RSI of 64 is neutral.
- **Beta (1 yr): 1.17** (volatility 130%). Beta of 1.17 against the S&P 500: the shares move roughly with the market.

Live score and charts: https://foliofundamentals.com/analyzer?s=PYXS · Page: https://foliofundamentals.com/stocks/pyxs

Not investment advice.