# Syndax Pharmaceuticals Inc. (SNDX) fundamentals

Data as of 2026-09-08. NASDAQ, United States. Sector: Healthcare / Biotechnology. Price $20.56, market value $1.8 billion.

## Valuation
- **P/E (trailing): n/a** (negative earnings). Syndax Pharmaceuticals Inc. reported negative earnings over the last twelve months, so the P/E is not meaningful; use price-to-sales, EV/EBITDA and free-cash-flow yield instead.
- **Price / sales: 7.3×**. Each dollar of revenue is priced at 7.3×.
- **Price / book: 121.7×**. The shares trade at 121.7× book value; most of the value is in earnings power and intangibles rather than the balance sheet.

## Profitability
- **Operating margin: -77.1%**. Operating margin is negative: the business loses money before interest and tax.
- **Net margin: -165.6%**. The company reported a net loss over the last twelve months.
- **Return on equity: -441.6%**. Return on equity is negative because earnings are negative.
- **Return on invested capital: -56.1%**. Return on all capital, debt included, is -56.1%: close to or below the cost of capital, so growth may not create value.
- **Return on assets: -41.7%**. Each dollar of assets produces -41.7% of profit.

## Growth
- **Revenue growth (1 yr): 627.8%** (5-yr 157.7%/yr). Revenue grew 627.8% over the last year, against 157.7% a year compounded over five years: growth is accelerating.
- **EPS growth (1 yr): 11.6%**. Earnings per share rose 11.6%, slower than revenue, so margins compressed.

## Financial health
- **Debt to equity: 5.32**. Debt is 5.32 times equity, a leveraged balance sheet that needs steady cash flow to service.
- **Altman Z-score: 1.16**. A Z-score of 1.16 is in the distress zone, a signal to examine the balance sheet closely.
- **Piotroski F-score: 1/9**. 1 of 9 checks pass: weak or deteriorating financials.

## Dividends
- **Dividend: none**. Syndax Pharmaceuticals Inc. does not currently pay a dividend.

## Price and momentum
- **Total return (1 yr): 27.0%** (YTD -2.1%, 3-mo 18.6%). The shares are up 27.0% over twelve months including dividends.
- **From 52-week high: -19.7%** (58.3% above the low). Trading 20% below its 52-week high.
- **200-day average: below**. The price sits below its 200-day moving average, the usual definition of a downtrend.
- **RSI (14-day): 53**. An RSI of 53 is neutral.
- **Beta (1 yr): 0.62** (volatility 51%). Beta of 0.62 against the S&P 500: the shares move much less than the market.

Live score and charts: https://foliofundamentals.com/analyzer?s=SNDX · Page: https://foliofundamentals.com/stocks/sndx

Not investment advice.